Key result
Cardioneuroablation for functional bradyarrhythmias lacks multicenter randomized data beyond one small published study.
Why the study?
The lack of multicenter, randomized trials prevents cardioneuroablation from being included in bradyarrhythmia treatment guidelines, with only one small randomized study published to date.
Does cardioneuroablation improve outcomes in patients with vagally mediated bradyarrhythmias?
Does cardioneuroablation improve outcomes in patients with vagally mediated bradyarrhythmias?
This review summarizes ongoing randomized controlled trials that aim to establish the effectiveness and safety of cardioneuroablation for vagally mediated bradyarrhythmias.
Cardioneuroablation should not yet change practice for functional bradyarrhythmias; leaves open efficacy and safety pending multicenter RCTs.
Cardioneuroablation is a rapidly developing procedure for the treatment of vagally mediated bradyarrhythmias. However, the lack of multicenter, randomized trials prevents it from being included in bradyarrhythmia treatment guidelines. So far, only one small, randomized study has been published assessing the effectiveness of this method in the treatment of reflex syncope. This is a brief review of ongoing randomized trials evaluating the effectiveness and safety of cardioneuroablation for the treatment of functional bradyarrhythmias.
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Skoczyński et al. (2025) conducted a review in Vagally mediated bradyarrhythmias. Cardioneuroablation was evaluated. Cardioneuroablation for the treatment of functional bradyarrhythmias currently lacks multicenter randomized trial data, with only one small published study to date.
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