Key result
A frontal QRS-T angle ≥ 100° was associated with an increased risk of sudden arrhythmic death (RR 2.26; 95% CI 1.59-3.21; P<0.001) in a middle-aged general population.
Why the study?
Does a wide frontal QRS-T angle (≥ 100°) predict death from arrhythmia in a middle-aged general population?
Cohort (n=10,957)
Does a wide frontal QRS-T angle (≥ 100°) predict death from arrhythmia in a middle-aged general population?
Effect estimate: RR 2.26 (95% CI 1.59-3.21)
p-value: p=< 0.001
A wide frontal QRS-T angle (≥ 100°) on a standard 12-lead ECG is a strong predictor of sudden arrhythmic death in the general middle-aged population.
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Hypothesis-generating for ECG risk stratification; requires prospective validation before clinical adoption.
Aro et al. (2011) conducted a cohort in General population (n=10,957). Frontal QRS-T angle ≥ 100° vs. Normal QRS-T angle (0 to 90°) was evaluated on Death from arrhythmia (RR 2.26, 95% CI 1.59-3.21, p=< 0.001). A frontal QRS-T angle ≥ 100° was associated with an increased risk of sudden arrhythmic death (RR 2.26; 95% CI 1.59-3.21; P<0.001) in a middle-aged general population.
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