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Pediatric patients with neurotic and hyperkinetic reaction patterns have been treated experimentally on one of 3 schedules: (a) brief psychotherapy, (b) brief psychotherapy plus placebo, (c) brief psychotherapy plus perphenazine. Analysis of the clinical response rates has led us to the following conclusions: 1. Children with neurotic symptomatology show a prompt and enduring response to a brief program of psychotherapy at a level of improvement (60-70%) that is significantly greater than that attained by children with hyperkinetic syndromes (15-40%). 2. No evidence was obtained for any enhancement of the response to brief psychotherapy from the addition of placebo medication. 3. We were unable to demonstrate a significant difference between response to placebo and to perphenazine when administered concomitantly with psychotherapy. The implications of these findings have been discussed.
Eisenberg et al. (Thu,) studied this question.