Language-related eligibility criteria in UK randomised trials: a systematic review of extended research reports

January 1, 2026Open Access

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Key Points

To investigate language-related eligibility criteria used in UK randomised trials and their implications on trial inclusivity.
Conducted a systematic review of extended research reports from randomised trials in the UK.
Analyzed the language-related eligibility criteria specified in the reports.
Included trials published in a defined timeframe to ensure relevance.
Identified significant variation in language-related eligibility criteria across trials.
Many trials imposed strict language requirements that could exclude non-native speakers.
Findings highlight a potential barrier to inclusivity in clinical research.

Systematic review uncovers language-related eligibility criteria in UK randomised trials, suggesting implications for inclusion processes.

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Isaacs et al. (2026) studied this question.

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