Choosing clinically interpretable summary measures and robust analytic procedures for quantifying the treatment difference in comparative clinical studies

The data that support the findings of the study in Section 2 are openly available in Goldman et al.7 at https://www.nejm.org/doi/10.1056/NEJMoa2015301. The data that support the findings of the study in Section 3 are openly available in Hellmann et al.15 at https://www.nejm.org/doi/10.1056/NEJMoa1910231 and Guyot et al.16 at http://doi.org/10.1186/1471-2288-12-9. The data that support the findings of the study in Section 4 are not publicly available.