Hematological and Biochemical Studies in Commercially Important Fish Labeo rohita Exposed to Cadmium Chloride

C admium chloride is a naturally elemental occurring component found in various organisms, rocks and soil. It is primarily insoluble in its trivalent form. While oxidation makes chromium chloride soluble, reduction keeps Cr insoluble in water Cadmium chloride, a prevalent metal, Abstract | The present study comes to assess how heavy metal (cadmium chloride) affects the hematological and biochemical parameters in the Labeo rohita (Rohu: Hamilton, 1822). Freshwater fishes Labeo rohita, (n = 60), with body weight (70-120 g), were randomly divided into four experimental groups Treatment T1, Treatment T2 and Treatment T3 (0.44mg/l, 0.89mg/l, and 1.34 mg/l), while the fourth group (T0) served as a control (0.00mg/l). Sampling was done on 7, 14 and 21-day. Results showed significant increase in WBC (white blood cell), whereas red blood cells count, Hb (hemoglobin) and Hct (hematocrit) were significantly reduced in treated groups compared to the control. The mean corpuscular hemoglobin (MHC) and mean corpuscular hemoglobin concentration (MCHC) showed a non-significant decrease in treated groups compared to the control group. Serum biochemical parameters, including total proteins, albumin and globulin, decreased significantly (p < 0.05). At the same time, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), glucose and cholesterol were significantly (p < 0.05) increased in the treated groups compared to the control group. In conclusion, the study indicates that exposure to cadmium chloride, even in a low concentration, can cause adverse hematological and biochemical changes in Labeo rohita.