Key result
Systemic inflammatory response syndrome (SIRS) immediately after oral cancer surgery was associated with a significantly higher rate of postoperative complications compared to non-SIRS (56.3% vs 8.3%).
Why the study?
Does the development of postoperative SIRS predict postoperative complications in oral cancer patients undergoing neck dissection?
Cohort (n=40)
No
Does the development of postoperative SIRS predict postoperative complications in oral cancer patients undergoing neck dissection?
The presence of SIRS for at least 24 hours postoperatively is a significant predictor of postoperative complications in oral cancer surgery.
Answers are grounded in this paper and cite their sources.
SIRS after oral cancer surgery was associated with higher complications; hypothesis-generating for monitoring trials before any practice change.
Systemic inflammatory response syndrome (SIRS) symptoms immediately after surgery have lately been regarded as potential warnings of impending postoperative complications and multiple organ failure. Reports discussing the relationship between operative stress and SIRS are found in the field of digestive surgery, but not in that of oral surgery. Forty oral cancer cases who had undergone neck dissection (Level III or higher) from January 1998 to June 1999 were involved in this study. We assigned 16 cases who met two of the several diagnostic criteria for SIRS and continued to meet them for at least 24 hours after surgery to the SIRS group. The other 24 patients were assigned to the non-SIRS group. Postoperative complications occurred in 56.3% of the SIRS group and 8.3% of the non-SIRS group (p<0.05). In two cases, the postoperative fluctuation of IL-6 level was evaluated. These results suggest the importance of careful management of postoperative SIRS patients to prevent complications.
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Yajima et al. (2000) conducted a cohort in Oral cancer (n=40). Systemic inflammatory response syndrome (SIRS) vs. Non-SIRS was evaluated on Postoperative complications (p=<0.05). Systemic inflammatory response syndrome (SIRS) immediately after oral cancer surgery was associated with a significantly higher rate of postoperative complications compared to non-SIRS (56.3% vs 8.3%).
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