Key result
Reduced left ventricular ejection fraction was significantly associated with a higher risk of all-cause mortality and heart failure rehospitalization following TAVI (adjusted HR 0.980).
Why the study?
The prognostic implications of low LVEF and its postoperative improvement in patients undergoing TAVI remain unclear.
Cohort (n=909)
No
Background: Previous studies have established low Left Ventricular Ejection Fraction (LVEF) as a significant predictor of poor prognosis across various cardiac conditions. However, the prognostic implications of low LVEF and its postoperative improvement in patients undergoing Transcatheter Aortic Valve Implantation (TAVI) remain unclear.
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Ishigaki et al. (2024) conducted a cohort in Severe aortic stenosis (n=909). Transcatheter Aortic Valve Implantation (TAVI) in patients with reduced LVEF (<40%) vs. TAVI in patients with preserved LVEF (≥50%) and mildly reduced LVEF (40-49%) was evaluated on Composite of all-cause mortality and heart failure rehospitalization (HR 0.980, 95% CI 0.966-0.995, p=0.008). Reduced left ventricular ejection fraction was significantly associated with a higher risk of all-cause mortality and heart failure rehospitalization following TAVI (adjusted HR 0.980).
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