Key result
Macrophage polarization is a dynamic, non-fixed process that exhibits sufficient plasticity to integrate multiple environmental signals from microbes and damaged tissues.
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Design
Review
Macrophage plasticity may inform evolving inflammatory responses in cardiovascular disease; leaves open targeted modulation strategies for future trials.
Macrophage polarization refers to how macrophages have been activated at a given point in space and time. Polarization is not fixed, as macrophages are sufficiently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and ...Read More
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Richard A. Murphy (1989) studied this question. Macrophage polarization is a dynamic, non-fixed process that exhibits sufficient plasticity to integrate multiple environmental signals from microbes and damaged tissues.
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