Multicomponent reactions (MCRs) have emerged as key green tool in organic synthesis for their methodological simplicity. MCRs have made heterocycle synthesis more versatile. The most crucial molecule among the most often used heterocycles is pyridine, which is widely used in biological, industrial, and pharmaceutical sectors. In light of this, our mini‐review highlights the literature on substituted pyridine synthesis published from the year 2016 to early 2022 via multicomponent approach.
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