Why the study?
Does unilateral cervicothoracic sympathetic ganglionectomy effectively treat Long QT Interval Syndrome?
Does unilateral cervicothoracic sympathetic ganglionectomy effectively treat Long QT Interval Syndrome?
This paper discusses unilateral cervicothoracic sympathetic ganglionectomy as a treatment approach for Long QT Interval Syndrome, a condition where standard antiarrhythmic therapy is often contraindicated.
Answers are grounded in this paper and cite their sources.
Insufficient evidence supports unilateral cervicothoracic sympathetic ganglionectomy for LQTS; controlled trials needed before adoption.
THE syndrome of congenital deafness, syncopal episodes, long QT interval on the electrocardiogram and sudden death has been well described.1 2 3 Recently, ventricular dysrhythmias have been documented as the cause of the syncope and sudden death in this condition.4 Although the original descriptions indicated that the syndrome was hereditable, sporadic, nonfamilial cases with and without associated deafness have been reported.5 The cause of the prolonged QT interval is poorly understood, but abnormalities in the central nervous system have been implicated.6 Effective antiarrhythmic therapy has been the subject of considerable interest since the prolonged QT interval contraindicates the use of most standard . . .
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Moss et al. (1971) studied Long QT Interval Syndrome. Unilateral Cervicothoracic Sympathetic Ganglionectomy was evaluated.
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