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October 14, 1971New England Journal of Medicine437 citations

Unilateral Cervicothoracic Sympathetic Ganglionectomy for the Treatment of Long QT Interval Syndrome

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AMArthur J. MossJMJoseph V. McDonald

Key Result

Unilateral cervicothoracic sympathetic ganglionectomy was discussed as a potential treatment for long QT interval syndrome, though specific clinical outcomes were not provided in the abstract.

Structured PICO

Does unilateral cervicothoracic sympathetic ganglionectomy effectively treat Long QT Interval Syndrome?

P
Population
Patients with Long QT Interval Syndrome (associated with congenital deafness, syncopal episodes, and sudden death)
I
Intervention
Unilateral Cervicothoracic Sympathetic Ganglionectomy

This paper discusses unilateral cervicothoracic sympathetic ganglionectomy as a treatment approach for Long QT Interval Syndrome, a condition where standard antiarrhythmic therapy is often contraindicated.

Abstract

THE syndrome of congenital deafness, syncopal episodes, long QT interval on the electrocardiogram and sudden death has been well described.1 2 3 Recently, ventricular dysrhythmias have been documented as the cause of the syncope and sudden death in this condition.4 Although the original descriptions indicated that the syndrome was hereditable, sporadic, nonfamilial cases with and without associated deafness have been reported.5 The cause of the prolonged QT interval is poorly understood, but abnormalities in the central nervous system have been implicated.6 Effective antiarrhythmic therapy has been the subject of considerable interest since the prolonged QT interval contraindicates the use of most standard . . .

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Cite This Study

Moss et al. (1971) studied Long QT Interval Syndrome. Unilateral Cervicothoracic Sympathetic Ganglionectomy was evaluated. Unilateral cervicothoracic sympathetic ganglionectomy was discussed as a potential treatment for long QT interval syndrome, though specific clinical outcomes were not provided in the abstract.

synapsesocial.com/papers/6a0cfb21b31ab1d6e01e750dhttps://doi.org/10.1056/nejm197110142851607
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