Key result
Higher Tei index linked to greater mortality in non-ischemic dilated cardiomyopathy.
Why the study?
Idiopathic DCM is a leading cause of low-EF heart failure, and the study aimed to investigate the relationship between the Tei index and long-term survival in non-ischemic DCM patients.
Does the Tei index predict long-term survival in patients with non-ischemic dilated cardiomyopathy?
Cohort (n=98)
Does the Tei index predict long-term survival in patients with non-ischemic dilated cardiomyopathy?
The Tei index is a useful echocardiographic marker that, especially when combined with LVEF, predicts long-term survival in patients with non-ischemic dilated cardiomyopathy.
May support Tei index for risk stratification in non-ischemic dilated cardiomyopathy; hypothesis-generating pending prospective validation.
AIM: Idiopathic dilated cardiomyopathy (DCM) is one of the leading causes of low ejection fraction (EF) heart failure (HF). The Tei index is a reliable marker that reflects both left ventricular (LV) systolic and diastolic function, and it has prognostic value in patients with DCM. We aimed to investigate the relationship between the Tei index and long-term survival in non-ischemic, DCM patients. MATERIAL AND METHODS: The present study included 98 patients with non-ischemic DCM. The mean survival time of the patients was 59 mos. RESULTS: The Tei index was prominently higher in patients who died (0.64±0.08 vs 0.71±0.12, respectively; p=0.01). LV end-systolic volume and LV ejection fraction (LVEF) were independent prognostic factors and predicted worse long-term survival. Additionally, the patients with LVEF ≥32.7 % and the Tei index ≤0.76 had significantly longer survival. CONCLUSION: The present study showed that the Tei index was significantly associated with mortality and the patients with both low LVEF (≤32.7 %) and high Tei index (≥0.76) values had a shorter life expectancy. As a result, we suggest that the Tei index may be a useful echocardiographic marker to predict long-term survival in DCM patients.
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Karabacak et al. (2023) conducted a cohort in Non-ischemic, dilated cardiomyopathy (n=98). Tei index was evaluated on Long-term survival / mortality (p=0.01). A higher Tei index was significantly associated with mortality in patients with non-ischemic dilated cardiomyopathy (0.71±0.12 in those who died vs 0.64±0.08 in survivors; p=0.01).
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