Prostate cancer detection in a clinical urological practice by ultrasonography, digital rectal examination and prostate specific antigen

No AccessJournal of Urology1 Feb 2002Prostate cancer detection in a clinical urological practice by ultrasonography, digital rectal examination and prostate specific antigen William H. Cooner, B.R. Mosley, Charles L. Rutherford, Jeff H. Beard, Harry S. Pond, William J. Terry, Todd C. Igel, and Donald D. Kidd William H. CoonerWilliam H. Cooner , B.R. MosleyB.R. Mosley , Charles L. RutherfordCharles L. Rutherford , Jeff H. BeardJeff H. Beard , Harry S. PondHarry S. Pond , William J. TerryWilliam J. Terry , Todd C. IgelTodd C. Igel , and Donald D. KiddDonald D. Kidd View All Author Informationhttps://doi.org/10.1016/S0022-5347(02)80313-5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail The prostate cancer detection rate from screening by digital rectal examination and tactilely guided prostate biopsy is approximately 1.7%. Among 1,807 men a detection rate of 14.6% was achieved in a clinical urological practice by physician-conducted prostate ultrasonography, digital rectal examination and determination of serum prostate specific antigen. Results are presented in 5-year increments as well as for the group as a whole. The possible benefit to be derived from an improved detection rate is undetermined. Recommendations are made regarding the clinical use of these diagnostic modalities. References 1. : The accuracy of the rectal examination in the diagnosis of prostate carcinoma. New Engl. J. Med.1980; 303: 499. Google Scholar 2. : Prostate cancer: comparison of transrectal US and digital rectal examination for screening. Radiology1988; 168: 389. Google Scholar 3. : Early detection of prostate cancer by routine screening. J.A.M.A.1984; 252: 3261. Google Scholar 4. : Treatment and survival of patients with cancer of the prostate. Surg., Gynec. & Obst.1967; 124: 1011. Google Scholar 5. : Approaches to chemotherapy of prostate cancer. Ad. Oncol.1988; 4: 18. Google Scholar 6. : An evaluation of serial digital rectal examinations in screening for prostate cancer. J. Urol.1988; 140: 1445. Link, Google Scholar 7. : Diagnosis of carcinoma of prostate. Urology1981; 17: 54. Google Scholar 8. : Physical examination: a revered skill under scrutiny. South. Med. J.1988; 81: 770. Google Scholar 9. : Tumor markers in cancer diagnosis and prognosis. CA1988; 38: 104. Google Scholar 10. : Daily variability in human serum prostate-specific antigen and prostatic acid phosphatase: a comparative evaluation. Urology1988; 32: 288. Google Scholar 11. : What's new in tumor markers for prostate cancer?. Urology1986; 27: 487. Google Scholar 12. : Prostate-specific antigen as a serum marker for adenocarcinoma of the prostate. New Engl. J. Med.1987; 317: 909. Crossref, Medline, Google Scholar 13. : Clinical application of transrectal ultrasonography and prostate specific antigen in the search for prostate cancer. J. Urol.1988; 139: 758. Link, Google Scholar 14. : Coordination of urosonography and prostate-specific antigen in the diagnosis of nonpalpable prostate cancer. J. Endourol.1989; 3: 193. Google Scholar 15. : The use of transrectal prostatic ultrasonography in the evaluation of patients with prostatic carcinoma. J. Urol.1989; 141: 233. Link, Google Scholar 16. chapt. 10 : Prostate cancer sonographic characteristics. In: Ultrasound of the Prostate. New York: Raven Press1988: 157. Google Scholar 17. : Patterns of progression in prostate cancer. Lancet1986; 1: 60. Crossref, Medline, Google Scholar 18. : Prostate specific antigen in the diagnosis and treatment of adenocarcinoma of the prostate. II. Radical prostatectomy treated patients. J. Urol.1989; 141: 1076. Link, Google Scholar 19. : Natural history and staging of prostate cancer. Urol. Clin. N. Amer.1984; 11: 205. Google Scholar 20. : Transrectal ultrasound study of prostate. Urology1988; 32: 401. Google Scholar 21. : Evaluation of prostate-specific antigen and prostatic acid phosphatase as prostate cancer markers. Urology1986; 28: 472. Crossref, Medline, Google Scholar 22. : An evaluation of prostate specific antigen in prostatic cancer. J. Urol.1987; 137: 686. Link, Google Scholar 23. chapt. 15 : On the sensitivity, specificity, and discrimination of diagnostic tests. In: Clinical Biostatistics. St. Louis: The C. V. Mosby Co.1977: 214. Google Scholar 24. : . Boston: Duxbury Press1982. Google Scholar 25. : Latent carcinoma of the prostate. J. Path. Bach.1954; 68: 603. Google Scholar 26. : On the frequency of occurrence of occult carcinoma of the prostate. J. Urol.1935; 33: 215. Link, Google Scholar 27. : Morphometric and clinical studies on 68 consecutive radical prostatectomies. J. Urol.1988; 139: 1235. Link, Google Scholar 28. : Transrectal ultrasound in management of prostate cancer. Urology1989; 33: 27. Google Scholar 29. : The appearance of prostate cancer on transrectal ultrasonography: correlation of imaging and pathological examinations. J. Urol.1989; 142: 76. Link, Google Scholar 30. : Incidental carcinoma of the prostate: an analysis of the predictors of progress. J. Urol.1988; 140: 1340. Link, Google Scholar 31. : Is grade or stage of primary importance in determining the outcome after radical prostatectomy for disease clinically confined to the prostate?. Brit. J. Urol.1989; 63: 301. Google Scholar 32. : Ultrasound guided transrectal core biopsies of the palpably abnormal prostate. J. Urol.1989; 142: 66. Link, Google Scholar 33. : Needle biopsy of the prostate: a re-evaluation. J. Urol.1962; 87: 164. Link, Google Scholar 34. : Carcinoma of the prostate: biopsy and conservative therapy. J. Urol.1972; 108: 897. Link, Google Scholar 35. : Confidence in the negative transrectal needle biopsy. Surg., Gynec. & Obst.1973; 136: 78. Google Scholar 36. : Ultrasound-guided and digitally guided biosies of the prostate. J. Endourol.1989; 3: 177. Google Scholar 37. : Prostate cancer XI. Early prostatic cancer diagnosed by arbitrary open perineal biopsy among 300 unselected patients. Cancer1954; 7: 690. Google Scholar 38. : Prostate specific antigen. Experimental and clinical observations. Scand. J. Urol. Nephrol.1987; 104: 33. Google Scholar 40. : The effect of digital rectal examination on serum levels of prostatic-specific antigen. Arch. Path. Lab. Med.1988; 112: 1110. Google Scholar 41. : Prostate-specific antigen in management of prostatic carcinoma. Urology1989; 33: 11. Google Scholar 42. : Prostate specific antigen in the diagnosis and treatment of adenocarcinoma of the prostate. I. Untreated patients. J. Urol.1989; 141: 1070. Link, Google Scholar 43. The management of clinically localized prostate cancer. In: National Institutes of Health Consensus Development Conference. : 1987: 1369. Google Scholar 44. : The ethics of the randomized clinical trial. New Engl. J. Med.1982; 307: 719. Google Scholar 45. : Transrectal ultrasonography: is it ready for routine use?. J.A.M.A.1988; 259: 2744. Google Scholar 46. : Cancer statistic, 1989. CA1989; 39: 3. Google Scholar 47. : Urology. J.A.M.A.1989; 261: 2896. Google Scholar References Bianchi, 1956 : Practical advantage of the perineal biopsy of the prostate. J. Urol.1956; 76: 645. Link, Google Scholar Parry and Finelli, 1960 : Biopsy of prostate. J. Urol.1960; 84: 643. Link, Google Scholar Spring and Alden, 1954 : An evaluation of the needle biopsy in the diagnosis of prostate carcinoma. Canad. Med. Ass. J.1954; 70: 179. Google Scholar References 1. : Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J. Urol.1989; 142: 71. Link, Google Scholar 2. : Stage A versus stage B adenocarcinoma of the prostate: morphological comparison and biological significance. J. Urol.1988; 139: 61. Link, Google Scholar 3. : Zonal distribution of prostatic adenocarcinoma: correlation with histologic pattern and direction of spread. Amer. J. Clin. Path.1988; 89: 897. Google Scholar 4. : Unsuspected adenocarcinoma of the prostate in patients undergoing cystoprostatectomy for other causes: incidence, histology and morphometric observations. J. Urol.1989; 141: 1091. Link, Google Scholar © 2002 by American Urological Association, IncFiguresReferencesRelatedDetailsCited byMoussa A (2012) Editorial CommentJournal of Urology, VOL. 188, NO. 4, (1150-1150), Online publication date: 1-Oct-2012. Volume 167Issue 2 Part 2February 2002Page: 966-974 Advertisement Copyright & Permissions© 2002 by American Urological Association, IncMetricsAuthor Information William H. Cooner More articles by this author B.R. Mosley More articles by this author Charles L. Rutherford More articles by this author Jeff H. Beard More articles by this author Harry S. Pond More articles by this author William J. Terry More articles by this author Todd C. Igel More articles by this author Donald D. Kidd More articles by this author Expand All Advertisement PDF downloadLoading ...