Key result
Autopsy reveals true ventricular aneurysm from atherosclerotic transmural MI in a 32-year-old sudden death victim.
Case Report (n=1)
No
This case report illustrates a fatal true ventricular aneurysm complicating an undiagnosed myocardial infarction in a young 32-year-old male.
Alerts clinicians to fatal aneurysm risk after silent MI in young adults; leaves open optimal screening strategies.
A ventricular aneurysm can be pseudo or true; it is a rare complication of myocardial infarction induced by an intra-myocardial dissecting hematoma due to fragile myocardium. Ventricular wall rupture takes place two to four days after myocardial infarction when coagulative necrosis and inflammatory infiltrate and lysis of myocardial connective tissue results in weakening of infarcted myocardium. Acute cardiac wall ruptures are mostly fatal; an unwittingly located pericardial adhesion can abort a rupture resulting in a false aneurysm. The wall of a false aneurysm consists of the epicardium in contrast to a true aneurysm, which is composed of the myocardium. True aneurysms are complications seen in transmural infarcts. Thinned-out scar tissue paradoxically bulged during systole, and toughened fibrotic wall rupture doesn't usually occur. Deaths in subjects with true ventricular aneurysms occur due to mural thrombus, arrhythmias, and heart failure. We encountered a case of a true aneurysm, as reported below.
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Meshram et al. (2022) conducted a case report in Myocardial Infarction with Ventricular Wall Aneurysm (n=1). Autopsy of a 32-year-old male who died suddenly revealed a true ventricular aneurysm resulting from a transmural myocardial infarction with severe atherosclerosis.
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