Key result
Mitral orifice occlusion revealed negative intraventricular pressures, demonstrating that the mammalian ventricle is capable of exerting a sucking force during diastole.
Why the study?
Does the mammalian ventricle exert a sucking force during diastole?
Does the mammalian ventricle exert a sucking force during diastole?
The study provides experimental evidence that the mammalian ventricle is capable of active diastolic suction to draw blood from the atrium.
Animal evidence supports ventricular suction; leaves open its role in human diastolic function and requires clinical validation.
Intraventricular pressures were measured during brief periods of mitral orifice occlusion to determine whether or not the ventricle can exert a sucking force during diastole. This procedure was based on the premise that with a wide open mitral orifice negative diastolic transmural pressures cannot be detected in the ventricle because the adjoining atrium has collapsible walls. During mitral orifice closure, negative intraventricular pressures were recorded, and Ringer's solution was sucked against the force of gravity into the ventricle. It is concluded that the mammalian ventricle is capable of sucking blood from the atrium into its cavity.
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Gerhard A. Brecher (1956) studied this question. Mitral orifice occlusion was evaluated on Intraventricular pressures during diastole. Mitral orifice occlusion revealed negative intraventricular pressures, demonstrating that the mammalian ventricle is capable of exerting a sucking force during diastole.
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