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May 16, 2026International Journal of Molecular SciencesOpen Access

Special Issue “Role of NRF2 Pathway in Chronic Diseases”

Ángel Juan García-Yagüe

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Key Points

This review aims to explore the role of the NRF2 pathway in various chronic diseases.
Literature review analyzing the role of NRF2 in metabolic, cardiovascular, neurodegenerative, and inflammatory disorders.
Describes the association between NRF2 activation and reduced chronic disease prevalence.
Highlights potential therapeutic strategies targeting NRF2 to mitigate chronic diseases.

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Implication

This review explores how NRF2 impacts chronic diseases, suggesting its potential therapeutic role.

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Cite This Study

Ángel Juan García-Yagüe (2026) studied this question.

synapsesocial.com/papers/6a0d4efcf03e14405aa9a2c6 https://doi.org/10.3390/ijms27104460

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1NRF2 in age-related musculoskeletal diseases: Role and treatment prospectsReview · 2023 · 35 citations
2Special Issue “Innovative Strategies to Target Metabolism, Inflammation, and Oxidative Stress in Human Diseases”Original Research · 2026
3The Role of NRF2 in Obesity-Associated Cardiovascular Risk Factorsreview · 2022 · 63 citations
4NRF2 as a guardian of health: from an ancient survival pathway to a modern therapeutic targetReview · 2026 · 8 citations
5Nrf2 Modulation by Natural Compounds in Aging, Neurodegeneration, and Neuropathic PainReview · 2026 · 12 citations

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