What does this research mean for the field?

Veno-venous extracorporeal membrane oxygenation (VV-ECMO) can successfully manage refractory hypoxemic respiratory failure secondary to cocaine-induced diffuse alveolar hemorrhage without prohibitive bleeding complications. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

What question did this study set out to answer?

Investigate the occurrence of diffuse alveolar hemorrhage (DAH) due to cocaine inhalation and its management.

May 20, 2026American Journal of Respiratory and Critical Care Medicine

A42-13 Cocaine Induced Diffuse Alveolar Hemorrhage Resulting in Fulminant Hypoxemic Respiratory Failure Requiring VV-ECMO

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Investigate the occurrence of diffuse alveolar hemorrhage (DAH) due to cocaine inhalation and its management.
Case report of a 38-year-old male with cocaine inhalation and hypoxemic respiratory failure.
Treatment included non-rebreather mask, BIPAP, intubation, and VV-ECMO due to refractory hypoxemia.
Diagnostic bronchoscopy and use of methylprednisolone were employed.
Patient required urgent VV-ECMO after 4 hours due to persistent hypoxemia.
Resolved bloody secretions by day 5; extubated on day 9 and decannulated on day 11.
Survival post-DAH management using VV-ECMO in previous cases shows a 100% survival to decannulation.

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Implication

Case report examines cocaine-induced alveolar hemorrhage causing hypoxemia, highlighting VV-ECMO's role in treatment.

Cite This Study

Isaac et al. (2026) studied this question.

synapsesocial.com/papers/6a0d4efcf03e14405aa9a36f https://doi.org/10.1093/ajrccm/aamag162.2949

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A42-13 Cocaine Induced Diffuse Alveolar Hemorrhage Resulting in Fulminant Hypoxemic Respiratory Failure Requiring VV-ECMO

Key Points

Discussion

Implication

Cite This Study

A42-13 Cocaine Induced Diffuse Alveolar Hemorrhage Resulting in Fulminant Hypoxemic Respiratory Failure Requiring VV-ECMO

Key Points

Discussion

Implication

Cite This Study

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