Near-complete genome sequences of equine herpesvirus (EHV) 1, EHV-3, and EHV-4 from the USA using a hybrid assembly approach

Q: What does this research mean for the field?

A hybrid assembly approach combining Illumina and Oxford Nanopore reads successfully yields high-quality, near-complete genome sequences of equine herpesvirus 1, 3, and 4 from the USA. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Tirth Uprety; Lutz S. Goehring; Aveen Rozhbayani; Allison Meyer; Stephanie Michelle Todd; Sahar Abdelrazek; Kevin Lahmers; Erdal Erol

doi:10.1128/mra.01347-25

May 18, 2026Microbiology Resource AnnouncementsOpen Access

Near-complete genome sequences of equine herpesvirus (EHV) 1, EHV-3, and EHV-4 from the USA using a hybrid assembly approach

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Key Points

The aim is to report nearly complete genome sequences of equine herpesviruses to enhance understanding of their diversity and evolution.
Utilized a hybrid assembly approach combining Illumina and Oxford Nanopore sequencing to generate genomes.
Collected samples of EHV-1, EHV-3, and EHV-4 from horses in the USA.
Achieved near-complete genome sequences for EHV-1, EHV-3, and EHV-4.
Demonstrated enhanced quality in genome assembly through hybrid techniques.

Implication

Reports near-complete genome sequences in equine herpesvirus, highlighting diversity and evolution.

Abstract

We report near-complete genome sequences of equine herpesvirus (EHV) 1, 3, and 4 from the USA. Hybrid assemblies combining Illumina and Oxford Nanopore reads yielded high-quality genomes, enhancing understanding of EHV diversity and evolution in the USA.

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Cite This Study

Uprety et al. (2026) studied this question.

synapsesocial.com/papers/6a0d4f34f03e14405aa9a6c4 https://doi.org/10.1128/mra.01347-25

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Near-complete genome sequences of equine herpesvirus (EHV) 1, EHV-3, and EHV-4 from the USA using a hybrid assembly approach

Key Points

Implication

Abstract

Discussion

Cite This Study

Near-complete genome sequences of equine herpesvirus (EHV) 1, EHV-3, and EHV-4 from the USA using a hybrid assembly approach

Key Points

Implication

Abstract

Discussion

Cite This Study

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