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May 20, 2026American Journal of Respiratory and Critical Care Medicine

B45-01 Clinical Outcomes of Patients With Non-Cystic Fibrosis Bronchiectasis

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Authors

AFA G FerreiraUniversidade Federal de GoiásPPP De Oliveira Alcantara PaniagoUniversidade Federal de GoiásIFI Akel de FariaUniversidade Federal de Goiás

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Overview

Retrospective cohort study analyzes outcomes in patients with non-cystic fibrosis bronchiectasis, suggesting azithromycin reduces exacerbations.

Key Points

  • The aim was to evaluate the clinical profile and outcomes of patients with non-cystic fibrosis bronchiectasis.
  • Retrospective single-center cohort study of 75 patients with non-cystic fibrosis bronchiectasis
  • Data collected included sociodemographic information, comorbidities, symptoms, medications, spirometry results, and sputum cultures
  • Statistical analyses included Mann-Whitney and Kruskal-Wallis tests for comparisons and chi-square tests for associations.
  • Continuous use of azithromycin significantly reduced exacerbations (chi-square=7.89, p=0.005)
  • Sputum culture positivity was not significantly related to sputum color (chi-square=3.77, p=0.288)
  • Chronic infection showed a significant association with sputum color (chi-square=8.72, p=0.033).

Cite This Study

Ferreira et al. (2026) studied this question.

synapsesocial.com/papers/6a0d4f92f03e14405aa9af1ahttps://doi.org/10.1093/ajrccm/aamag162.1229
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