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May 20, 2026Autophagy0 citations

Identification of a conserved receptor for degrading ribosomes through autophagy

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CGChhabi K. GovindOakland UniversityDKDaniel J. KlionskyUniversity of Michigan

Key Points

  • The aim is to identify a receptor that mediates the degradation of ribosomes through the autophagy process.
  • Investigated the role of Atg8-family interacting motifs in ribosome autophagy.
  • Analyzed the interaction between NUFIP1 and ribosomes within cellular systems.
  • Identified a conserved receptor essential for targeting ribosomes for degradation.
  • Established that NUFIP1 interacts with ribosomes and is crucial for their autophagic degradation.

Abstract

AIM: Atg8-family interacting motif; ATG: autophagy related; LIR: LC3-interacting region; NUFIP1: nuclear FMR1 interacting protein 1.

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Cite This Study

Govind et al. (2026) studied this question.

synapsesocial.com/papers/6a0d5051f03e14405aa9bf7bhttps://doi.org/10.1080/15548627.2026.2624242
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