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May 20, 2026American Journal of Respiratory and Critical Care Medicine0 citations

C40-30 Treatment-Associated Renal Impairment in Multisystem Sarcoidosis Case

C40-30 Treatment-Associated Renal Impairment in a Patient With Multisystem Sarcoidosis

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Authors

JCJ P CorcoranLCL CrowleyMHM Hadaya

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Overview

Case report demonstrates renal dysfunction linked to treatment in a patient with multisystem sarcoidosis, suggesting careful management is essential.

Key Points

  • This case aims to illustrate the challenges in managing renal impairment associated with treatment in multisystem sarcoidosis.
  • A 61-year-old man with newly diagnosed pulmonary sarcoidosis and complex autoimmune history was monitored after treatment adjustments.
  • Renal biopsy and brain MRI were utilized to assess for treatment-related renal injury and neurologic manifestations.
  • Therapeutic interventions included the discontinuation of IVIG and initiation of methotrexate.
  • Renal biopsy revealed immunoglobulin deposition without granulomas, indicating IVIG-associated nephropathy.
  • Patient exhibited ongoing neurologic symptoms requiring careful management of immunosuppressive therapy.
  • Treatment adjustments aimed to balance neurologic control with renal protection and overall immunosuppressive burden.

Cite This Study

Corcoran et al. (2026) studied this question.

synapsesocial.com/papers/6a0d5051f03e14405aa9bfe4https://doi.org/10.1093/ajrccm/aamag162.2714
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