Case describes diagnosis and treatment of granulomatosis with polyangiitis in a woman with complex lung lesions, indicating the need for vigilant monitoring.
Key Points
To highlight the diagnostic challenges and treatment effectiveness for granulomatosis with polyangiitis (GPA), particularly when presenting with isolated lung lesions.
Case report of a 59-year-old woman with respiratory symptoms and imaging findings suggestive of GPA.
Biopsies and laboratory tests were conducted to identify granulomatous inflammation and confirm GPA diagnosis.
Treatment involved corticosteroids, methotrexate, and intravenous cyclophosphamide for management of systemic involvement.
Initial biopsies showed focal necrosis without malignancy, and corticosteroids led to partial regression of lung lesions.