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May 20, 2026American Journal of Respiratory and Critical Care Medicine

A60-04 Accuracy of Fractional Exhaled Nitric Oxide (FeNO) in Detecting Bronchial Asthma in Children With Congenital Heart Disease

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Authors

CAC G AgudoMRM Requiron-Sy

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Overview

Randomized trial evaluates FeNO's diagnostic accuracy for asthma in children with congenital heart disease, suggesting clinical benefits.

Key Points

  • To evaluate the accuracy of Fractional Exhaled Nitric Oxide (FeNO) in diagnosing bronchial asthma among children with congenital heart disease.
  • Prospective cross-sectional study involving 28 pediatric patients with congenital heart disease referred for pre-operative evaluation.
  • Both FeNO testing and spirometry were performed at bedside using standardized criteria.
  • FeNO levels were compared to spirometry findings to assess diagnostic performance.
  • FeNO threshold of > 11 ppb showed 100% sensitivity and 95.83% specificity for asthma diagnosis.
  • Overall diagnostic accuracy of FeNO was 96.43%, while spirometry parameters did not significantly differentiate groups.
  • Positive predictive value was 80% and negative predictive value was 100%.

Cite This Study

Agudo et al. (2026) studied this question.

synapsesocial.com/papers/6a0d50cdf03e14405aa9ce16https://doi.org/10.1093/ajrccm/aamag162.352
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