Key result
FDG PET/CT shows intense uptake reaching SUVmax ~44 in primary bilateral adrenal dedifferentiated liposarcoma.
Why the study?
Primary adrenal liposarcoma is very rare, and primary bilateral adrenal liposarcoma is even rarer.
Case Report (n=1)
Dedifferentiated liposarcoma should be included in the differential diagnosis of FDG-avid bilateral adrenal lesions.
Should be considered in the differential for FDG-avid bilateral adrenal masses; single-case data leaves open need for validation.
Primary adrenal liposarcoma is very rare, accounting for only 0.2% of primary adrenal tumors. Primary bilateral adrenal liposarcoma is even rarer. We describe FDG PET/CT findings in a case of primary bilateral adrenal dedifferentiated liposarcoma. The bilateral adrenal tumors showed intense FDG uptake with SUVmax of 32 and 44 for the right and left adrenal tumors, respectively. This case indicates that dedifferentiated liposarcoma should be included in the differential diagnosis of FDG-avid bilateral adrenal lesions, including adrenocortical carcinoma, pheochromocytoma, lymphoma, metastasis, and infection.
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Dai et al. (2026) conducted a case report in Primary bilateral adrenal dedifferentiated liposarcoma (n=1). FDG PET/CT was evaluated on FDG uptake (SUVmax). FDG PET/CT of primary bilateral adrenal dedifferentiated liposarcoma showed intense FDG uptake with SUVmax of 32 and 44 for the right and left adrenal tumors, respectively.
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