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May 20, 2026American Journal of Respiratory and Critical Care Medicine

B80-6-15 When Immunotherapy Takes One Lung: A Rare Case of Unilateral Granulomatous Pneumonitis

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Authors

DDD DuongACA R ConfortiKBK Bird

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Overview

Case report finds granulomatous pneumonitis in a male lung cancer patient treated with immunotherapy, suggesting potential treatment pathways.

Key Points

  • This report examines a rare case of unilateral granulomatous pneumonitis induced by pembrolizumab in a lung cancer patient.
  • Case study of a 61-year-old male with stage IV lung cancer and a lung mass following chemotherapy.
  • Utilized navigational bronchoscopy and endobronchial ultrasound for diagnosis.
  • Patient treated with a prednisone taper alongside levofloxacin.
  • Granulomatous pneumonitis diagnosed with no malignant cells present.
  • Post-treatment CT imaging showed resolution of pneumonitis with residual scarring.
  • Oncology discontinued pembrolizumab due to the adverse event.

Cite This Study

Duong et al. (2026) studied this question.

synapsesocial.com/papers/6a0d5100f03e14405aa9d3b0https://doi.org/10.1093/ajrccm/aamag162.2966
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