Key result
High pulse pressure linked to ~34% higher odds of restrictive and obstructive pulmonary disease.
Why the study?
Impaired pulmonary function is associated with arterial stiffness, of which pulse pressure is an important predictor, but the association between impaired pulmonary function and pulse pressure was unclear.
Is high pulse pressure associated with impaired pulmonary function in non-smoking adults?
Cross-Sectional (n=6,857)
Is high pulse pressure associated with impaired pulmonary function in non-smoking adults?
High pulse pressure is independently associated with both restrictive and obstructive pulmonary disease in non-smoking adults, suggesting a link between arterial stiffness and impaired lung function.
High pulse pressure may mark impaired lung function in non-smokers; leaves open causality and need for longitudinal confirmation.
According to previous studies, an impaired pulmonary function is associated with arterial stiffness (AS). The pulse pressure (PP) is an important predictor of AS, but the association of an impaired pulmonary function with the PP is unclear. Therefore, this study assessed the associations between the PP and the predicted forced vital capacity (predicted FVC) and predicted forced expiratory volume in one second (predicted FEV1) in Korean non-smoking adults. The data obtained from 6,857 adults during the 20132015 Korean National Health and Nutrition Examination Survey were analyzed. After adjusting for the related variables, the ORs of restrictive pulmonary disease (RPD, the predicted FVC80.0% with FEV1/FVC70.0%) using the normal PP group (PP60 mmHg) as a reference group was significant for the high PP group (PP60 mmHg; 1.337 [95% confidence interval (CI), 1.0491.703]). In addition, the ORs of obstructive pulmonary disease (OPD, FEV1/FVC70.0%) using the normal PP group as a reference group were significant for the high PP group (1.339 [95% CI, 1.0931.642]). In conclusion, a high PP is positively associated with both RPD and OPD in Korean non-smoking adults.
No takes yet. Share an insight, caveat, or question.
Hyun Yoon (2020) conducted a cross-sectional in Impaired pulmonary function (n=6,857). High pulse pressure vs. Normal pulse pressure was evaluated on Restrictive pulmonary disease (RPD) (OR 1.337, 95% CI 1.049-1.703). High pulse pressure was significantly associated with increased odds of restrictive pulmonary disease (OR 1.337; 95% CI 1.049-1.703) and obstructive pulmonary disease (OR 1.339; 95% CI 1.093-1.642).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: