Endovascular treatment with non-covered stents for complex aortic dissection significantly increased the mean minimal true lumen diameter from 10.55 mm to 27.38 mm and achieved a 0% mortality rate.
Observational (n=36)
No
Does endovascular uncovered stent implantation improve aortic remodeling and survival in patients with acute aortic dissection and end-organ ischemia?
Endovascular treatment with uncovered stents for complex aortic dissection with malperfusion is safe, induces positive aortic remodeling, and is associated with excellent survival.
Absolute Event Rate: 27.38% vs 10.55%
p-value: p=<0.001
Background: We present an analysis that compares aortic morphological and clinical outcomes of 36 patients, all treated with endovascular uncovered stents implantation preceded or not by stent-graft implantation, or surgical treatment in the context of complex treatment of type A or type B aortic dissection. Methods: Between 2014 and 05/2018 our team treated 36 patients with acute aortic dissection and end-organ ischemia due to true lumen compression. All clinical and periprocedural data were obtained prospectively, followed by a retrospective analysis. The case series aim is to show induction of aortic remodeling by depressurization of the false lumen and increasing the size of the true lumen by non-covered stents implantation in the aorta and its affected side branches. Secondary endpoints were survival, branch patency, true lumen and false lumen size evolution. Results: Results from the diameter of both lumens measured by computed tomography angiography (CTA) before and at least 1 year after the treatment showed statistically significant differences, patent stents, as well as symptomatic improvement in all patients. Both aorta-related and general mortality in this complex group of patients was 0%. Conclusions: The concept of redirection of flow in aortic dissection with non-covered stents was safe, led to positive aorta remodeling and resulted in excellent survival rate.
Petrov et al. (Thu,) conducted a observational in Acute aortic dissection with end-organ ischemia (n=36). Endovascular uncovered stent implantation vs. Baseline was evaluated on Minimal true lumen diameter (mm) (95% CI 12.45-21.34, p=<0.001). Endovascular treatment with non-covered stents for complex aortic dissection significantly increased the mean minimal true lumen diameter from 10.55 mm to 27.38 mm and achieved a 0% mortality rate.