Research on the renin-angiotensin-aldosterone system and adrenergic mechanisms provided the foundation for therapeutic attenuation of cardiac remodeling after acute myocardial infarction.
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Dr Rutherford asks: In the early 1970s, you, and your late wife Janice, studied adrenergic mechanisms and cardiac hypertrophy and ventricular function, as well, in spontaneously hypertensive rats. What led to your initial animal studies on acute myocardial infarction and your interest in the renin-angiotensin-aldosterone system?
Pfeffer et al. (Mon,) reported a other. Research on the renin-angiotensin-aldosterone system and adrenergic mechanisms provided the foundation for therapeutic attenuation of cardiac remodeling after acute myocardial infarction.