Neuropathology of cerebral ischemia and hypoxia: Recent advances in experimental studies on its pathogenesis

Cerebral hypoxia and ischemia are two of the most common disorders of the central nervous system. The pathomechanism has been a focus of interest in neuroscience for many years not only because of the clinical significance but also because of the peculiar distribution of the lesion (selective vulnerability) depending on the type of injury. This article reviews recent advances in the study of hypoxia-induced tissue injury of the central nervous system.