Chemical update on the potential for serotonin 5-HT6 and 5-HT7 receptor agents in the treatment of Alzheimer’s disease

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Phases of Aβ-deposition in the human brain and its relevance for the development of AD2002 · 3,614 citations
2. 2How long can patients with mild or moderate Alzheimer’s dementia maintain both the cognition and the therapy of cholinesterase inhibitors: a national population‐based study2008 · 73 citations
3. 3Synthesis and biological evaluation of novel N1-phenylsulphonyl indole derivatives as potent and selective 5-HT6R ligands for the treatment of cognitive disorders2016 · 2 citations
4. 4Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β2018 · 361 citations