What question did this study set out to answer?

To establish normative effective diameter reference standards and z-score formulas for the thoracic aorta, abdominal aorta, and common iliac arteries across pediatric and young adult populations.

December 3, 2014Radiology

Determining the Normal Aorta Size in Children

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Authors

SHShilpa HegdeChildren's Minnesota SLShelly LensingSt. Jude Children's Research Hospital SGS. Bruce GreenbergAllegheny College

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Implication

Retrospective study establishes normal pediatric aorta diameter reference standards and z-score formulas, enabling precise detection of vascular aneurysms and hypoplasia.

Key Points

To establish normative effective diameter reference standards and z-score formulas for the thoracic aorta, abdominal aorta, and common iliac arteries across pediatric and young adult populations.
Retrospectively analyzed contrast-enhanced CT scans from 88 thoracic and 110 abdominal examinations in cardiovascularly normal individuals aged 0 to 20 years (mean age 9.9 years; BSA range 0.19–2.52 m²).
Two radiologists independently measured effective diameters across multiple aortic and iliac levels using 1-mm double-oblique reconstructions, followed by ordinary least squares regression modeling against body surface area and sex.
Interrater reliability between readers was high across all measurement sites, with correlation coefficients ranging from 0.95 to 0.98.
The best-fitting model was a polynomial regression of the natural log of effective diameter incorporating linear, quadratic, and cubic body surface area terms alongside sex to generate expected diameter and z-score equations.

Cite This Study

Hegde et al. (2014) studied this question.

synapsesocial.com/papers/6a0db15ccecdf5fb20ba8fd5 https://doi.org/10.1148/radiol.14140500

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Implication

Retrospective study establishes normal pediatric aorta diameter reference standards and z-score formulas, enabling precise detection of vascular aneurysms and hypoplasia.

Determining the Normal Aorta Size in Children

Discussion

Member takes

Implication

Key Points

Cite This Study

Determining the Normal Aorta Size in Children

Discussion

Member takes

Implication

Key Points

Cite This Study

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