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November 1, 1972Cardiovascular Research685 citations

Forward and backward waves in the arterial system

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NWNicolaas WesterhofPSP. SipkemaGBG. C. van den Bos

Key Result

Altering peripheral resistance in dogs demonstrated that arteriolar reflections contribute a highly variable amount to the returning wave, while large vessel bifurcations contribute a constant amount.

Structured PICO

P
Population
Arterial system of the dog
I
Intervention
High and low peripheral resistance, and an occluded descending aorta
C
Comparator
Control condition
O
Outcome
Total amount of reflection in the arterial system (forward and backward waves of pressure and flow)surrogate

The study demonstrates that aortic pressure and flow can be separated into forward and backward waves, highlighting the variable contribution of arteriolar reflections to arterial hemodynamics.

Abstract

The total amount of reflection in the arterial system of the dog is evaluated during control, high, and low peripheral resistance, and an occluded descending aorta. Pressure, as measured in the ascending aorta, may be separated into a (composite) wave travelling from the heart towards the periphery, the forward wave, and a (composite) wave that travels in the opposite direction, the backward wave. This is also true for aortic flow. One may distinguish between reflections at bifurcations of the large vessels and reflections at the arteriolar part of the arterial tree. The former contribute a small, rather constant amount to the returning wave, while the latter reflects a strongly variable amount.

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Cite This Study

Westerhof et al. (1972) studied this question. Altered peripheral resistance and aortic occlusion vs. Control was evaluated on Total amount of reflection in the arterial system. Altering peripheral resistance in dogs demonstrated that arteriolar reflections contribute a highly variable amount to the returning wave, while large vessel bifurcations contribute a constant amount.

synapsesocial.com/papers/6a0db3ac6e03bc61cb09e23bhttps://doi.org/10.1093/cvr/6.6.648
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Multiple Wave Reflections In The Systemic Arterial System2005 · 2 citations
  2. 2Repeated reflection of waves in the systemic arterial system1993 · 70 citations
  3. 3Method for determining distribution of reflection sites in the arterial system1996 · 20 citations
  4. 4Calculation of Forward and Backward Arterial Waves by Analysis of Two Pressure Waveforms2010 · 25 citations
  5. 5Negative wave reflections in pulmonary arteries2001 · 84 citations