Key result
Benzodiazepines and smoking linked to up to ~16-fold higher delirium risk in elderly femoral fracture patients.
Case-Control (n=62)
Effect estimate: OR 5 (sedatives), OR 16 (smoking)
Highlights potential modifiable delirium risks in elderly femoral neck fracture patients; leaves open causality pending prospective confirmation.
Delirium is a common complication in hospitalized elderly patients suffering from hip fractures. Considering the growing incidence of delirium, understanding the risk factors for this condition is of great importance. The preoperative prevalence of delirium is approximately 4.4–35.6%, while postoperative prevalence is even higher - 4–53.3%. Various studies have shown the multifactorial etiology of delirium arising from a combination of predisposing and precipitating factors. The aim of this study was to explore these factors, which can contribute to delirium in patients with femoral neck fractures. This case control study included 62 patients diagnosed with femoral neck fractures, with 31 cases and 31 controls. Results have shown that the use of sedatives, especially benzodiazepines, and smoking increase the risk of delirium by five and sixteen times, respectively.
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Milićević et al. (2017) conducted a case-control in Femoral neck fractures and delirium (n=62). Sedatives and smoking vs. Controls was evaluated on Delirium (OR 5 (sedatives), OR 16 (smoking)). The use of sedatives, especially benzodiazepines, and smoking increased the risk of delirium by five and sixteen times, respectively, in elderly patients with femoral neck fractures.
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