Outcome of Endoscopic Treatment for Vesicoureteral Reflux in Children Using Polydimethylsiloxane

No AccessJournal of UrologyPEDIATRIC UROLOGY1 Nov 2002Outcome of Endoscopic Treatment for Vesicoureteral Reflux in Children Using Polydimethylsiloxane ADEL A. AL-HUNAYAN, ELIJAH O. KEHINDE, MAMDOUH A. ELSALAM, and ROLA S. AL-MUKHTAR ADEL A. AL-HUNAYANADEL A. AL-HUNAYAN Requests for reprints: Section of Urology, Department of Surgery, Faculty of Medicine, Kuwait University, P.O. Box 24923, Safat 13110, Kuwait. More articles by this author , ELIJAH O. KEHINDEELIJAH O. KEHINDE More articles by this author , MAMDOUH A. ELSALAMMAMDOUH A. ELSALAM More articles by this author , and ROLA S. AL-MUKHTARROLA S. AL-MUKHTAR More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64349-2AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We reviewed the outcome of subureteral injection of polydimethylsiloxane as a bulking agent for endoscopic treatment for vesicoureteral reflux in patients younger than 12 years. Materials and Methods: A total of 40 children (59 ureters) with primary grades II to IV vesicoureteral reflux were treated with a single subureteral injection from 1997 to 2001 and followed an average of 26 months (range 4 to 45). Results in 38 patients (55 ureteral units) were available for review. Each child underwent preoperative voiding cystourethrography, renal ultrasound, dimercapto-succinic acid scan and urine culture. Treatment was done on an outpatient basis. With the patient general anesthesia polydimethylsiloxane implant was injected transurethrally below the ureteral opening of the affected renal unit. Renal ultrasound at 1 week and voiding cystourethrography at 2 months were done to rule out obstruction at the injection site and/or persistent reflux, respectively. Cure was defined as absent vesicoureteral reflux on voiding cystourethrography 2 months after injection. Results: After a single injection polydimethylsiloxane cured vesicoureteral reflux in 45 ureteral units (81.8%), while in 5 (9.1%) the condition was improved. The remaining 5 ureteral units (9.1%) showed no change in reflux grade. In 1 patient (1.9%) with unilateral grade IV vesicoureteral reflux contralateral reflux developed. None of the cured patients had recurrent reflux during followup. In 1 patient ureteral obstruction was successfully treated with ureteral reimplantation. Conclusions: Endoscopic subureteral injection of polydimethylsiloxane implant in children with primary grades II to IV vesicoureteral reflux appears to be an effective, safe and minimally invasive technique. References 1 : Possible causes of unsuccessful endoscopic collagen treatment of vesicoureteric reflux in children. Eur Urol1999; 36: 635. Google Scholar 2 : Treatment of vesicorenal reflux by transurethral teflon-injection. Urologe A1981; 20: 263. Google Scholar 3 : Treatment of vesicoureteric reflux by endoscopic injection of Teflon. Brit Med J1984; 289: 7. Google Scholar 4 : Migration and granulomatous reaction after periurethral injection of polytef (Teflon). JAMA1984; 251: 3277. Google Scholar 5 : Endoscopic treatment of reflux: migration of Teflon to the lungs and brain. Eur Urol1993; 23: 394. 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Link, Google Scholar From the Department of Pediatric Surgery, Bin Sina Hospital, Section of Urology, Department of Surgery, Mubarek Al-Kabeer Hospital and Faculty of Medicine, Kuwait University, Safat, Kuwait© 2002 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byVandersteen D, Routh J, Kirsch A, Scherz H, Ritchey M, Shapiro E, Wolpert J, Pfefferle H and Reinberg Y (2018) Postoperative Ureteral Obstruction After Subureteral Injection of Dextranomer/Hyaluronic Acid CopolymerJournal of Urology, VOL. 176, NO. 4, (1593-1595), Online publication date: 1-Oct-2006.SIMSEK F, YUCEL S, AKTAS M and TURKERI L (2018) Ordinary Glass Spheres as an Alternative Injectable Material for Endoscopic Correction of Vesicoureteral RefluxJournal of Urology, VOL. 171, NO. 3, (1282-1286), Online publication date: 1-Mar-2004. Volume 168Issue 5November 2002Page: 2181-2183 Advertisement Copyright & Permissions© 2002 by American Urological Association, Inc.Keywordsureterendoscopydimethylpolysiloxanesvesico-ureteral refluxprostheses and implantsMetricsAuthor Information ADEL A. AL-HUNAYAN Requests for reprints: Section of Urology, Department of Surgery, Faculty of Medicine, Kuwait University, P.O. Box 24923, Safat 13110, Kuwait. More articles by this author ELIJAH O. KEHINDE More articles by this author MAMDOUH A. ELSALAM More articles by this author ROLA S. AL-MUKHTAR More articles by this author Expand All Advertisement PDF downloadLoading ...