Key result
Higher renal resistive index is linked to greater CIMT in patients with diabetic microalbuminuria.
Why the study?
Assessing the carotid artery alongside renal resistive index measurement was evaluated for potential benefit in early diagnosis and treatment of diabetic complications.
Does renal resistive index (RRI) correlate with carotid intima media thickness (CIMT) for the early detection of atherosclerosis in patients with diabetic microalbuminuria?
Observational (n=108)
No
Does renal resistive index (RRI) correlate with carotid intima media thickness (CIMT) for the early detection of atherosclerosis in patients with diabetic microalbuminuria?
p-value: p=<0.001
Renal resistive index correlates positively with carotid intima-media thickness and may serve as an adjunctive surrogate marker for early atherosclerosis detection in patients with diabetic microalbuminuria.
Supports RRI as adjunctive atherosclerosis marker in diabetic microalbuminuria; hypothesis-generating, needs prospective validation.
Diabetes is a chronic disease with increasing morbidity and mortality. Microalbuminuria is seen in diabetic patients due to nephropathy. Patients with microalbuminuria are at high risk for atherosclerosis. It is thought that comparing the carotid artery, which is most frequently affected by atherosclerosis, by measuring and comparing the renal resistive index, may be beneficial for early diagnosis and treatment of diabetic complications. Our study included 108 patients with diabetic microalbuminuria. Carotid intima media thickness (CIMT) and renal resistive index (RRI) measured, who applied to Adana Numune Training and Research Hospital between January and November 2016. We aimed to evaluate the patients with normal-abnormal RRI and normal-abnormal CIMT. The patients' diabetes age, weight, height, fasting blood sugar, HbA1c, and creatinine parameters were compared. We observed an increase in RRI in parallel with the increase in CIMT in diabetic microalbuminuric patients (p<0,001). There was also a positive correlation between the creatinine value and the RRI (p:0.021). The increase in creatinine was significantly associated with the increase in CIMT(p<0.001). However, we could not detect the similar correlation with body mass index (BMI) in terms of both RRI andCIMT. RRI measurement can be performed together with CIMT measurement for early detection of atherosclerosis. Patients with microalbuminuria and prone to atherosclerosis that cannot be detected by measurement of CIMT can be detected by measurement of the RRI.
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Bozan et al. (2021) conducted an observational in Diabetic microalbuminuria (n=108). Renal resistive index (RRI) measurement vs. Carotid intima media thickness (CIMT) measurement was evaluated on Correlation between renal resistive index (RRI) and carotid intima media thickness (CIMT) (p=<0.001). In patients with diabetic microalbuminuria, an increase in renal resistive index was significantly correlated with an increase in carotid intima media thickness (p<0.001).
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