Adult-onset diabetics without significant coronary disease or heart failure exhibited a significantly higher left ventricular end-diastolic pressure/volume ratio compared to controls.
Observational (n=26)
No
Does familial adult-onset diabetes mellitus affect left ventricular hemodynamics compared to controls?
This study investigates the presence of noncoronary cardiomyopathy in adult-onset diabetics by assessing left ventricular hemodynamics.
Absolute Event Rate: 0.097% vs 0.062%
p-value: p=<0.005
A C T Recent epidemiologic studies have suggested that cardiac disease is common in diabetics and may often have a noncoronary basis. To examine the status of the left ventricle, 17 adult-onset diabetics of familial type without hypertension or obesity under- went hemodynamic study and were compared to 9 controls of similar age.
Regan et al. (1977) conducted an observational in Familial Diabetes Mellitus (n=26). Diabetes Mellitus (Exposure) vs. Nondiabetic controls was evaluated on Left ventricular end-diastolic pressure/volume ratio (p=<0.005). Adult-onset diabetics without significant coronary disease or heart failure exhibited a significantly higher left ventricular end-diastolic pressure/volume ratio compared to controls.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: