Why the study?
Does familial adult-onset diabetes mellitus affect left ventricular hemodynamics compared to controls?
Observational (n=26)
No
Does familial adult-onset diabetes mellitus affect left ventricular hemodynamics compared to controls?
This study investigates the presence of noncoronary cardiomyopathy in adult-onset diabetics by assessing left ventricular hemodynamics.
Answers are grounded in this paper and cite their sources.
May indicate subclinical LV stiffness in adult-onset diabetes; leaves open clinical relevance pending prospective studies.
A C T Recent epidemiologic studies have suggested that cardiac disease is common in diabetics and may often have a noncoronary basis. To examine the status of the left ventricle, 17 adult-onset diabetics of familial type without hypertension or obesity under- went hemodynamic study and were compared to 9 controls of similar age.
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Regan et al. (1977) conducted an observational in Familial Diabetes Mellitus (n=26). Diabetes Mellitus (Exposure) vs. Nondiabetic controls was evaluated on Left ventricular end-diastolic pressure/volume ratio (p=<0.005).
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