Does Mini-Percutaneous Nephrolithotomy Cause Increased Intrarenal Pressure During Percutaneous Nephrolithotomy and is This Mitigated by a Suctioning Sheath? A Randomized Control Trial

Compared with balloon dilation, coaxial dilation with mPCNL sheaths generates significantly higher IRP. During nephroscopy, ns-mPCNL sheaths generate higher IRP compared with standard and suctioning sheaths. Highest IRPs are generated during RPG and when a nephroscope goes through a narrow infundibulum. These findings can inform improved sheath and nephroscope design. Further research assessing the effect of high IRP on postoperative pain, sepsis, and renal injury is needed.