Key result
The abstract proposes a hypothesis to predict low left atrial appendage emptying velocities and thrombus in patients undergoing AF ablation on uninterrupted warfarin, but reports no results.
Why the study?
Can clinical characteristics and transthoracic echocardiography predict low LAA emptying velocities or thrombus in patients undergoing AF ablation on uninterrupted warfarin?
Observational
Can clinical characteristics and transthoracic echocardiography predict low LAA emptying velocities or thrombus in patients undergoing AF ablation on uninterrupted warfarin?
The study hypothesizes that clinical characteristics and TTE can predict low LAA emptying velocities and thrombus in patients undergoing AF ablation on uninterrupted warfarin.
Hypothesis that TTE and clinical features predict LAA velocities or thrombus remains untested; prospective validation required before any clinical use.
Introduction: The 2012 HRS/EHRA/ECAS guidelines encourage pre-procedural transesophageal echocardiography (TEE) prior to ablation for atrial fibrillation (AF), but acknowledge a lack of consensus in patients maintained on therapeutic warfarin before, during and after the procedure. This is partly because the incidence of left atrial appendage (LAA) thrombus is so low, that it is hard to draw clear conclusion regarding the characteristics of patients who develop thrombus. We hypothesize that the presence of low LAA emptying velocities, which predisposes to thrombus, and/or thrombus itself can be predicted in patients undergoing ablation, based upon clinical characteristics and transthoracic echocardiography (TTE).
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Herring et al. (2013) conducted an observational in Atrial Fibrillation. Transthoracic echocardiography (TTE) and clinical characteristics was evaluated on Presence of low LAA emptying velocities and/or thrombus. The abstract proposes a hypothesis to predict low left atrial appendage emptying velocities and thrombus in patients undergoing AF ablation on uninterrupted warfarin, but reports no results.
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