Case 1: A 35-year-old man with a normal white blood cell (WBC) count (9.3 × 10 9 /L) was diagnosed with acute myeloid leukemia (AML) with a t(8;21)(q22;q22) translocation in 25/25 metaphases. The RUNX1-RUNX1T1 fusion gene was detected by real-time quantitative polymerase chain reaction (PCR),
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Käyser et al. (2015) studied this question.
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