A Controlled Clinical Trial of a Diet High in Unsaturated Fat

THERE is a wealth of information demonstrating a significant correlation between the concentration of plasma cholesterol — particularly, beta-lipoprotein cholesterol — and the risk of coronary heart disease. For a number of reasons, it is widely believed that this is a cause- and-effect relation dependent in large measure upon the fact that beta-lipoprotein is atherogenic. The idea has further grown that western man has, typically, an excessive amount of circulating cholesterol and other lipids, owing in major part to his habitual consumption of a diet rich in fat, particularly fat of animal origin. The evidence for these concepts has been . . .