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March 24, 2023Frontiers in Physiology19 citationsOpen Access

Conduction system pacing in pediatric and congenital heart disease

HCHenry ChubbDMDouglas Y. MahADAnne M. Dubin

Key Result

Conduction system pacing, including His bundle and left bundle branch area pacing, is emerging as a feasible and potentially superior alternative to conventional pacing in pediatric and congenital heart disease patients.

Structured PICO

Does conduction system pacing improve outcomes compared to conventional pacing in children and patients with congenital heart disease?

P
Population
Children and patients with congenital heart disease (CHD)
I
Intervention
Conduction system pacing (CSP), including His Bundle Pacing (HBP) and Left Bundle Branch Area Pacing (LBBAP)
C
Comparator
Conventional pacing techniques
O
Outcome
Feasibility and efficacy of conduction system pacing

Conduction system pacing, including His Bundle Pacing and Left Bundle Branch Area Pacing, is emerging as a feasible and potentially superior pacing strategy for pediatric and congenital heart disease patients.

Limitations

  • Limited data and small sample sizes in pediatric and congenital heart disease populations
  • Concerns regarding long-term lead parameters and extraction
  • Lack of randomized controlled trials demonstrating superiority in hard outcomes
  • Technical challenges and learning curve associated with implantation

Abstract

Conduction system pacing (CSP) has evolved rapidly to become the pacing method of choice for many adults with structurally normal hearts. Studies in this population have repeatedly demonstrated superior hemodynamics and outcomes compared to conventional pacing with the recruitment of the native conduction system. Children and patients with congenital heart disease (CHD) are also likely to benefit from CSP but were excluded from original trials. However, very recent studies have begun to demonstrate the feasibility and efficacy of CSP in these patients, with growing evidence that some outcomes may be superior in comparison to conventional pacing techniques. Concerns regarding the technical challenges and long-term lead parameters of His Bundle Pacing (HBP) have been overcome to many extents with the development of Left Bundle Branch Area Pacing (LBBAP), and both techniques are likely to play an important role in pediatric and CHD pacing in the future. This review aims to assimilate the latest developments in CSP and its application in children and CHD patients.

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Cite This Study

Chubb et al. (2023) conducted a review in Pediatric and congenital heart disease. Conduction system pacing (His Bundle Pacing and Left Bundle Branch Area Pacing) vs. Conventional pacing was evaluated. Conduction system pacing, including His bundle and left bundle branch area pacing, is emerging as a feasible and potentially superior alternative to conventional pacing in pediatric and congenital heart disease patients.

synapsesocial.com/papers/6a0e9be6a7f61df77cc86e07https://doi.org/10.3389/fphys.2023.1154629
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