Natural History of Ischemic Heart Disease in Relation to Arteriographic Findings

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Ischemic Heart Disease (n=224). Intervention: Severity of atherosclerotic disease of the coronary arteries. Primary outcome: Survival.

J. O’Neal Humphries; Lewis H. Kuller; Richard S. Ross; Gottlieb C. Friesinger; E Page

doi:10.1161/01.cir.49.3.489

March 1, 1974CirculationOpen Access

Natural History of Ischemic Heart Disease in Relation to Arteriographic Findings

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Key Points

To evaluate the relationship between the severity of coronary atherosclerotic disease visualized on arteriography and long-term survival in young patients with stable ischemic heart disease.
Followed a cohort of 224 young patients (mean age 41.8 years) without hypertension or congestive heart failure who underwent coronary arteriography during a stable disease phase.
Tracked patient survival outcomes over a follow-up interval ranging from 5 to 12 years (vital status ascertained for 218 of 224 patients [97%]).
Atherosclerotic disease severity in the coronary arteries significantly predicted survival over 5 to 12 years of follow-up.
Vital status was successfully ascertained in 97% (n=218/224) of the evaluated cohort.

Study Design

Type

Cohort (n=224)

PICO

P

Population

Ischemic Heart Disease (n=224)

I

Intervention / Comparator

Severity of atherosclerotic disease of the coronary arteries

O

Primary Outcome

Survival

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Cite This Study

Humphries et al. (1974) conducted a cohort in Ischemic Heart Disease (n=224). Severity of atherosclerotic disease of the coronary arteries was evaluated on Survival.

synapsesocial.com/papers/6a0e9dfe53f874f2b2228f72 https://doi.org/10.1161/01.cir.49.3.489

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Natural History of Ischemic Heart Disease in Relation to Arteriographic Findings

Key Points

Study Design

PICO

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Abstract

Discussion

Cite This Study

Natural History of Ischemic Heart Disease in Relation to Arteriographic Findings

Key Points

Study Design

PICO

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Abstract

Discussion

Cite This Study

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