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May 21, 2026Journal of Eating DisordersOpen Access

Olfactory function and an explanatory model of pica revealed through a case report

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Authors

PBPedro Miguel BarbosaMRMariana RemelheLRLúcia Ribeiro

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Overview

Case report shows olfactory cravings leading to pica in an individual with iron deficiency anemia, suggesting new explanations.

Key Points

  • This case aims to understand the relationship between altered olfactory function and pica, specifically in a patient with iron deficiency anemia.
  • Clinical presentation of a 56-year-old woman with pica and iron deficiency anemia.
  • Detailed observations of her abnormal eating behaviors and olfactory cravings.
  • Proposed a neurochemical model to explain the onset and perpetuation of pica.
  • The patient developed cravings for bricks, indicated by a pleasant olfactory experience.
  • She exhibited symptoms of anxiety when attempting to stop eating bricks, despite recognizing the health risks.
  • This case highlights how altered olfactory function may contribute to the development and maintenance of pica behaviors.

Cite This Study

Barbosa et al. (2026) studied this question.

synapsesocial.com/papers/6a0ea074be05d6e3efb5f281https://doi.org/10.1186/s40337-025-01408-6
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