Key result
Two-stage CNN detects AF on Holter ECGs with ~93% accuracy, outperforming conventional single-stage methods.
Why the study?
AF can cause cardiac complications such as stroke, making early detection important.
A two-stage deep learning approach incorporating R-R interval variation extraction before 1D CNN analysis improves the accuracy of automated atrial fibrillation detection from Holter ECGs.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for automated AF detection; requires validation in larger cohorts before clinical use.
Atrial fibrillation (AF) is a type of arrhythmia that can cause cardiac complications such as stroke, and early detection is therefore important. This study proposes a method for detecting AF from the Holter electrocardiogram (ECG). The AF detection procedure has two stages: arrhythmia extraction based on the R-R interval variation and AF identification from the extracted arrhythmia using a one-dimensional convolutional neural network (1D CNN). Artifacts in the ECG are eliminated through preprocessing using a finite-impulse-response bandpass filter. In the first stage, R waves are detected through a multi-resolution analysis of the ECG, and arrhythmias are extracted by observing the standard deviation of the R-R intervals. In the second stage, AF is identified from the extracted arrhythmic events using a 1D CNN trained using segmented ECG waveforms. An ECG dataset of 100,000 segments obtained from the Holter ECG is prepared for training the CNN. Evaluation using 24-h ECG data from 10 untrained subjects verifies that the performance of the proposed detection method is better than that of the methods without arrhythmia extraction, with an accuracy of 93.1%. This result indicates the feasibility of the proposed method for detecting AF.
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Kamozawa et al. (2024) studied Atrial Fibrillation (n=252). Two-stage AF detection method (arrhythmia extraction + 1D CNN) vs. Single-stage AF detection method (1D CNN without arrhythmia extraction) was evaluated on Accuracy of AF detection on Holter ECG dataset. The proposed two-stage method using arrhythmia extraction and a 1D convolutional neural network detected atrial fibrillation from Holter ECGs with 93.1% accuracy, outperforming the conventional single-stage method.
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