Key result
1D blood flow simulation using two peripheral measurements estimates central aortic pressure within ~0.5 mmHg.
Why the study?
Can central arterial pressure be accurately estimated using one-dimensional blood flow simulation based on two peripheral pressure measurements?
Observational (n=62)
Can central arterial pressure be accurately estimated using one-dimensional blood flow simulation based on two peripheral pressure measurements?
One-dimensional arterial flow simulations using radial and carotid pressure measurements can accurately estimate central aortic pressure.
Supports noninvasive central pressure estimation; leaves open prospective clinical validation.
Aortic pressure can be estimated using one-dimensional arterial flow simulations. This study demonstrates that two peripheral pressure measurements can be used to acquire the central pressure curve through the patient-specific optimization of a set of system parameters. Radial and carotid pressure measurements and parameter optimization were performed in the case of 62 patients. The two calculated aortic curves were in good agreement, Systolic and Mean Blood Pressures differed on average by 0.5 and -0.5 mmHg, respectively. Good agreement was achieved with the transfer function method as well. The effect of carotid clamping is demonstrated using one resulting patient-specific arterial network.
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Gyürki et al. (2023) reported an observational. Central arterial pressure estimation using 1D blood flow simulation vs. Transfer function method was evaluated on Difference in calculated Systolic and Mean Blood Pressures. Central arterial pressure estimation using 1D blood flow simulation and two peripheral measurements yielded aortic curves with systolic and mean blood pressure differences of 0.5 and -0.5 mmHg.
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