What question did this study set out to answer?

To compare the five-year clinical outcomes of African American and Caucasian patients following percutaneous coronary intervention (PCI).

March 26, 2008Catheterization and Cardiovascular Interventions

Comparison of five‐year outcome in African Americans versus Caucasians following percutaneous coronary intervention

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Why the study?

Does African American ethnicity predict worse long-term outcomes compared to Caucasian ethnicity in patients undergoing PCI?

Population

730 consecutive patients undergoing percutaneous coronary intervention at a single tertiary care center in…

Comparison

African American ethnicity vs Caucasian ethnicity

Design

Cohort

Follow-up

5 years

Authors

JPJyotiranjan PradhanWayne State University TSTheodore SchreiberInterventional / Structural Cardiology ANAshutosh NirajInterventional / Structural Cardiology

Discussion

Member takes

Implication

Post-PCI African American patients may need enhanced surveillance; leaves open whether targeted strategies reduce disparities.

Key Points

To compare the five-year clinical outcomes of African American and Caucasian patients following percutaneous coronary intervention (PCI).
730 patients undergoing PCI were followed up for five years.
Patients' end points included all-cause mortality and first hospital admission for myocardial infarction, congestive heart failure, or revascularization.
Survival analysis utilized Kaplan-Meier methods and Cox regression for hazard ratio adjustments.
At five-year follow-up, African Americans had a lower survival rate (41%) compared to Caucasians (54%), log rank P 0.01.
Overall, African Americans experienced a higher incidence of acute myocardial infarction and congestive heart failure.
Adjusted hazard ratio for African American ethnicity as a predictor of adverse outcomes was 1.62 (95% CI 1.01-1.28, P 0.04).

Structured PICO

Does African American ethnicity predict worse long-term outcomes compared to Caucasian ethnicity in patients undergoing PCI?

Population

730 consecutive patients (67% African American) undergoing percutaneous coronary intervention (PCI) at a single tertiary care center in Detroit, MI

Intervention

African American ethnicity

Comparator

Caucasian ethnicity

Outcome

Composite of all-cause mortality or first hospital admission due to myocardial infarction (MI), congestive heart failure (CHF), and revascularization (PCI or CABG)composite

African American patients undergoing PCI have comparable short-term outcomes but significantly worse 5-year clinical outcomes compared to Caucasians, even after adjusting for confounders.

Cite This Study

Pradhan et al. (2008) studied this question.

synapsesocial.com/papers/6a0ec3a425c30b2cc7f9bfde https://doi.org/10.1002/ccd.21556

Topics

Women and heart disease

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Comparison of five‐year outcome in African Americans versus Caucasians following percutaneous coronary intervention

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Comparison of five‐year outcome in African Americans versus Caucasians following percutaneous coronary intervention

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider