Why the study?
Does aspirin prevent cardiovascular disease in primary prevention?
Population
Individuals considered for primary prevention of cardiovascular disease, particularly older adults
Design
Editorial
Authors
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The authors argue that recent guidelines restricting aspirin for primary prevention in older adults are based on flawed interpretations of the ASPREE trial and recommend individualized risk-benefit assessments instead.
Does aspirin prevent cardiovascular disease in primary prevention?
The authors argue that recent guidelines restricting aspirin for primary prevention in older adults are based on flawed interpretations of the ASPREE trial and recommend individualized risk-benefit assessments instead.
Wittes et al. (2025) conducted an editorial in Primary prevention of cardiovascular disease. Aspirin was evaluated. Aspirin for primary prevention of cardiovascular disease should be prescribed based on individual benefit-to-risk assessment rather than strict age cutoffs of <70 or <60 years.
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