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March 1, 1978Circulation373 citations

Recurrent sustained ventricular tachycardia. 2. Endocardial mapping.

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MJMark E. JosephsonLHLeonard N. HorowitzAFArdeshir Farshidi

Key Result

Endocardial ventricular mapping in 17 patients localized all 10 VT-RBBB to the LV or septum and 11 VT-LBBB to the RV, LV, or septum, demonstrating limitations of surface ECG.

Study Design

Type

Observational (n=17)

Structured PICO

Does endocardial ventricular mapping accurately localize the site of origin of ventricular tachycardia compared to surface ECG?

P
Population
17 patients with recurrent sustained ventricular tachycardia (21 VTs mapped)
I
Intervention
Endocardial ventricular mapping using electrode catheters
C
Comparator
Surface electrocardiogram
O
Outcome
Site of origin of the ventricular tachycardiasurrogate

Endocardial ventricular mapping provides more accurate localization of the site of origin of ventricular tachycardia than surface ECG, providing important data for surgical therapy.

Abstract

Endocardial ventricular mapping of 21 ventricular tachyardias (VT) in 17 patients was performed using electrode catheters. Activation at multiple left and right ventricular sites was utilized to determine the site of origin of the VT. Eleven VT had a left bundle branch block pattern (VT-LBBB) and 10 VT had right bundle branch block pattern (VT-RBBB). In all VT-RBBB the earliest site of activation was in the LV or septum. In VT-LBBB the earliest site was RV (4/11), LV (5/11) and septum (2/11). All ventricular tachycardias with QRS less than 140 msec arose in the septum. In patients with an aneurysm, the site of origin of ventricular tachycardia was always in the aneursm. All VT-LBBB arising from the left ventricle originated in an aneurysm involving the septum. QRS changes during ventricular tachycardia were associated with alterations in the patterm of ventricular activation without alteration of the site of origin. In three patients the site of origin predicted by endocardial ventricular mapping was confirmed intraoperatively by epi- and/or endocardial mapping. We conclude that endocardial ventricular mapping demonstrates the limitations of the surface electrocardiogram in localizing the site of origin of ventricular tachycardia. The method may provide important data upon which the surgical therapy of ventricular tachycardia is based.

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Cite This Study

Josephson et al. (1978) conducted an observational in Recurrent sustained ventricular tachycardia (n=17). Endocardial ventricular mapping was evaluated on Site of origin of ventricular tachycardia. Endocardial ventricular mapping in 17 patients localized all 10 VT-RBBB to the LV or septum and 11 VT-LBBB to the RV, LV, or septum, demonstrating limitations of surface ECG.

synapsesocial.com/papers/6a0ecb291c5e2d2319f9e133https://doi.org/10.1161/01.cir.57.3.440
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Surgical treatment of ventricular tachycardia after epicardial mapping studies.1975 · 132 citations
  2. 2Catheter mapping of retrograde atrial activation. Observations during ventricular pacing and AV nodal re-entrant paroxysmal tachycardia.1976 · 73 citations
  3. 3Subendocardial origin of ventricular arrhythmias in 24-hour-old experimental myocardial infarction.1976 · 125 citations
  4. 4Wolff-Parkinson-White syndrome. The problem, evaluation, and surgical correction.1975 · 392 citations
  5. 5Electrophysiology of the Heart1962 · 75 citations