Key result
A computer simulation of excitation in an anatomically based model of the human ventricular conduction system successfully recreated the gross features of activation sequences estimated from whole heart measurements.
An anatomically based computer model successfully simulated the excitation sequence of the human ventricular conduction system, matching whole heart measurements.
Accurately simulates ventricular conduction activation; extends modeling capabilities while leaving open clinical validation.
The simulation of excitation in a model whose gross physical characteristics are representative of the human ventricular conduction system is discussed. This objective was realized, and the resultant behavior reproduced the major features of a sequence estimated from previous work. Further, simulations were performed in a reasonable period of time. The activation sequence following a stimulus to the atrioventricular node was compared to a sequence estimated from a synthesis of whole heart measurements reported by other investigators. The gross features of the estimated sequence are recreated in the activation sequence simulated with the model.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
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Pollard et al. (2003) studied Human ventricular conduction system. Computer simulation of excitation vs. Estimated sequence from whole heart measurements was evaluated on Activation sequence following a stimulus to the atrioventricular node. A computer simulation of excitation in an anatomically based model of the human ventricular conduction system successfully recreated the gross features of activation sequences estimated from whole heart measurements.
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