What is the clinical evidence from this study?

Study design: Review. Population: Atrial fibrillation. Primary outcome: One-year mortality.

What question did this study set out to answer?

To evaluate the clinical course, mortality patterns, and prognostic determinants across different presentations of atrial fibrillation.

January 12, 1984Acta Medica Scandinavica

Atrial Fibrillation—a Review of Course and Prognosis

View Full Paper

Ask AI

Bookmark

Key result

A review of four major studies found that one-year mortality in atrial fibrillation ranged from 0.2% to 16.0%, and the overall rate of thromboembolic complications was approximately 25%.

Key Points

To evaluate the clinical course, mortality patterns, and prognostic determinants across different presentations of atrial fibrillation.
Reviewed four major clinical studies examining prognostic outcomes in atrial fibrillation.
Assessed mortality variation, incidence of thromboembolic events, and the prophylactic utility of coumarin anticoagulants across patient subgroups.
One-year mortality ranged from 0.2% in young individuals with paroxysmal disease without underlying heart disease to 16.0% in elderly, hospitalized patients with chronic atrial fibrillation.
Three studies indicated that outcomes in lone atrial fibrillation are worse than historically estimated, with an overall thromboembolic complication rate of approximately 25%.
The clinical efficacy of coumarin therapy in preventing thromboembolic events remained unproven across the evaluated literature.

Structured PICO

Population

Patients with atrial fibrillation (based on a review of 4 major studies)

Outcome

Prognosis (mortality and thromboembolic complications)hard clinical

The prognosis of atrial fibrillation is determined by age, type of AF, and clinical status, with lone AF having a poorer prognosis than previously thought and a high rate of thromboembolic complications.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Supports individualized AF risk assessment; leaves open need for updated prospective data in contemporary cohorts.

Cite This Study

Petersen et al. (1984) conducted a review in Atrial fibrillation. A review of four major studies found that one-year mortality in atrial fibrillation ranged from 0.2% to 16.0%, and the overall rate of thromboembolic complications was approximately 25%.

synapsesocial.com/papers/6a0eda5f218372ada647c741 https://doi.org/10.1111/j.0954-6820.1984.tb03763.x

Topics

Atrial fibrillation Persistent AF management Anticoagulation in AF AF ablation outcomes

View Full Paper

Ask AI

Bookmark

Atrial Fibrillation—a Review of Course and Prognosis

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Atrial Fibrillation—a Review of Course and Prognosis

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider